Polyethylene Glycol (PEG)-1500, with CAS No. 25322-68-3, is a linear polyether with an average molecular weight of 1500. It typically appears as a white solid powder or flakes, featuring excellent water solubility, low toxicity, non-ionic properties, and good chemical stability.
Widely used as a pharmaceutical excipient, cosmetic ingredient, and food additive, it serves multiple key functions: acting as a plasticizer to enhance flexibility, a binder for formulation cohesion, a lubricant to prevent sticking, a humectant to retain moisture, and a dispersant to ensure uniform mixing. Its low irritation and compatibility make it reliable in pharmaceuticals, skincare, food processing, and coating industries.
Product Advantage
1. Ultra-High Purity Meeting International Pharmacopoeia Standards
Our PEG-1500 achieves a purity of ≥99.5%, with impurity content (such as ethylene glycol and diethylene glycol) strictly controlled below 0.1%. It fully complies with the quality requirements of international pharmacopoeias including USP, EP, and BP, ensuring safe application in pharmaceutical, food, and cosmetic fields without introducing harmful substances.
2. Stable Physical & Chemical Properties with Narrow Molecular Weight Distribution
With a narrow molecular weight distribution (polydispersity index ≤1.05), our PEG-1500 maintains consistent performance in different batches. It remains stable at temperatures ranging from -20℃ to 60℃, without decomposition or discoloration, and shows excellent compatibility with most organic/inorganic substances. This stability reduces formulation risks for customers and improves product yield by over 5%.
3. Low Irritation & High Biocompatibility for Sensitive Scenarios
Toxicity tests confirm that our PEG-1500 has an LD50 (oral, rat) >5000 mg/kg, classified as non-toxic. Skin and mucosal irritation tests show zero irritation reactions, making it suitable for sensitive applications like oral tablets, eye drops, and baby skincare products. Its high biocompatibility also avoids adverse reactions in long-term use, winning trust from medical and cosmetic brands.
4. Versatile Functional Adaptability Across Multiple Industries
Beyond core functions like plasticizing, binding, and lubrication, our PEG-1500 can be customized for specific industry needs. For example, in pharmaceutical coating, it reduces tablet sticking rate to <0.3%; in food processing, it extends product shelf life by 30% as a humectant; in coatings, it improves film leveling property by 15%. This versatility lowers customers’ need for multiple additives, cutting procurement costs.
5. Strict Quality Control with Full Traceability System
Each batch of PEG-1500 undergoes 12+ quality inspections (including purity, molecular weight, moisture, and pH) before leaving the factory, with a qualified rate of 100% for 5 consecutive years. We provide a complete traceability report covering raw material sources, production processes, and inspection data, allowing customers to track product information in real time and meet regulatory audit requirements easily.
Technical Parameters
| Parameter | Details |
| Appearance | White waxy solid |
| Color | ≤50 |
| Hydroxyl value | 68~83 |
| Molecular Weight | 1350~1650 |
| pH Value | 4.5-7.0 |
| Purity | ≥ 99.0% |
Product Uses
1. Pharmaceutical Industry (Oral & Topical Preparations)
As a key pharmaceutical excipient, it’s used in oral tablets/capsules: acts as a binder to improve powder cohesion, a lubricant to prevent die sticking (reducing defect rate), and a coating material to enhance tablet stability. Also added to topical ointments to adjust consistency and boost drug solubility.
2. Cosmetic & Skincare Products
Applied in creams, lotions, and lipsticks: works as a humectant to lock in moisture (extending skin hydration for 4-6 hours), a plasticizer to keep lipsticks soft, and a solubilizer to blend oil-water ingredients. Suitable for sensitive skin products due to low irritation.
3. Food Processing
Used in baked goods, candies, and dairy products: acts as a humectant to prevent staling (extending shelf life by 20-30%), a plasticizer to improve candy chewiness, and a lubricant in powdered food to prevent caking. Complies with food-grade standards (e.g., FDA regulations).
4. Coating & Paint Industry
Added to water-based coatings and paints: functions as a dispersant to keep pigments uniformly distributed (avoiding sedimentation), a plasticizer to enhance film flexibility (reducing cracking), and a leveling agent to improve surface smoothness of coated products.
5. Plastic & Rubber Processing
Serves as an internal lubricant in PVC and rubber production: reduces friction between polymer molecules during processing, lowers melting temperature (saving energy by 8-10%), and improves product surface gloss without affecting mechanical properties.
Product Operate Guide
Preparation: For solid formulations (e.g., tablets), mix PEG-1500 powder with other excipients at 20-25℃ (avoid high humidity). For liquid systems (e.g., creams), dissolve it in warm water (40-50℃) first, then stir into the base.
Dosage: Typically 2-10% of total formulation (adjust per needs: e.g., 3-5% as lubricant, 5-8% as humectant).
Storage: Keep in sealed, dry containers away from direct sunlight. Use within 24 months of production for best performance.
FAQ
Q: Can PEG-1500 be mixed with ionic ingredients?
A: Yes. It is non-ionic, so it has good compatibility with most ionic substances (e.g., ionic surfactants in cosmetics) without causing precipitation or performance loss.
Q: What if PEG-1500 absorbs moisture and clumps?
A: Mild clumps can be crushed into powder manually and used normally (moisture absorption doesn’t affect its properties). For severe clumping, dry it at 40-50℃ for 1-2 hours before use.
Q: Is PEG-1500 safe for long-term use in food/cosmetics?
A: Yes. It meets USP/EP/FDA standards, has low toxicity (LD50 >5000 mg/kg), and no irritation, making it safe for long-term application in regulated food and cosmetic products.
Q: Can PEG-1500 replace PEG-400/PEG-6000 in formulations?
A: Not directly. Its molecular weight (1500) is between them—PEG-400 (liquid) suits solvents, while PEG-6000 (hard solid) suits binders. Choose based on your formulation’s texture and function needs.
