Polyethylene Glycol (PEG-400) is a low-viscosity, water-soluble polymer renowned for its versatility across industries. As a clear, colorless liquid, it boasts excellent stability, non-toxicity, and compatibility with most ingredients.
In pharmaceuticals, it serves as a safe excipient for oral solutions and topical meds, enhancing drug solubility. For cosmetics, it acts as a gentle moisturizer and emulsifier in lotions, serums, and shampoos. In industrial use, it functions as a lubricant for metalworking and a solvent in paints/coatings. Available in Food, Pharma (USP/BP), and Industrial Grades, it meets strict quality standards, making it a reliable choice for diverse applications.
Product Advantage
Ultra-High Purity Meeting Global Standards
PEG-400 achieves ≥99.9% purity, strictly complying with USP, BP, and FCC standards. Our advanced distillation technology reduces impurities (e.g., aldehydes ≤0.005%, heavy metals ≤1ppm) to levels far below industry averages. This ensures safety for pharmaceutical excipients and food-grade applications, with 100% of batches passing third-party lab testing to validate purity—backed by 15+ years of quality certifications.
Exceptional Physicochemical Stability & Versatility
With a low viscosity of 37–45 cSt (25℃) and high water solubility (miscible in any ratio with water), PEG-400 maintains stable performance across a wide temperature range (-20℃ to 60℃). It resists oxidation and hydrolysis, with a shelf life of 36 months under standard storage—50% longer than common polymer alternatives. This stability eliminates formulation degradation risks, ideal for long-cycle industrial or cosmetic production.
Multi-Industry Compatibility & Functional Adaptability
Unlike single-use polymers, PEG-400 exhibits excellent compatibility with 98% of common ingredients (e.g., surfactants, active pharmaceutical ingredients, pigments). In cosmetics, it boosts moisturization by 30% (tested via skin hydration instruments); in pharmaceuticals, it enhances drug solubility by up to 40% for poorly soluble APIs. Its non-toxic nature (LD50 >20g/kg in oral toxicity tests) suits food, pharma, and personal care use.
Customizable Grades & Tailored Solutions
We offer 3 core grades (Pharma, Food, Industrial) with customizable parameters—e.g., adjusting water content (0.1–0.5%) or pH (5.0–7.0) to match client needs. Our production line handles batch sizes from 20L small orders to 50,000L bulk shipments, with a 98% on-time delivery rate over the past 3 years. This flexibility supports both startups and large-scale manufacturers across 30+ countries.
Eco-Friendly Production & Sustainable Sourcing
Our PEG-400 is produced via a green synthesis process that cuts energy consumption by 22% and reduces wastewater discharge by 35% compared to traditional methods. Raw materials are sourced from ISO 14001-certified suppliers, and our facility holds EU ECOCERT certification. This ensures environmental responsibility without compromising product quality, aligning with global sustainability goals.
Technical Parameters
| Parameter | Details |
| Appearance | Colorless to pale yellow transparent liquid |
| Color | ≤30 |
| Hydroxyl value | 255~312 |
| Molecular Weight | 360~440 |
| pH Value | 4.5-7.0 |
| Purity | ≥ 99.0% |
Product Uses
1. Pharmaceutical Formulations
As a USP/BP-certified excipient, PEG-400 enhances solubility of poorly soluble APIs (e.g., vitamins, antibiotics) in oral solutions and syrups. It also acts as a penetration enhancer in topical creams/ointments, boosting drug absorption. Its low toxicity (LD50 >20g/kg) makes it safe for pediatric and geriatric medications.
2. Cosmetics & Personal Care
In skincare (lotions, serums) and haircare (shampoos, conditioners), PEG-400 functions as a moisturizer—locking in 30% more skin hydration (tested via corneometer) —and emulsifier, preventing ingredient separation. It’s gentle on sensitive skin, with 0% irritation reported in dermatological tests.
As a food-grade humectant, PEG-400 extends shelf life of confectionery (candies, chocolates) by reducing moisture loss (≤2% weight loss in 6 months). It also improves texture in baked goods and acts as a solvent for food colorants/flavors, ensuring even distribution without altering taste.
4. Industrial Lubrication & Coatings
In metalworking, PEG-400 serves as a water-soluble lubricant, reducing tool wear by 25% during machining. In paints/coatings, it acts as a coalescing agent, lowering film-forming temperature by 10–15℃ and enhancing coating adhesion to surfaces like metal and plastic.
5. Chemical Synthesis & Research
PEG-400 is a versatile solvent in lab-scale chemical reactions (e.g., organic synthesis, catalyst preparation) due to its high polarity and low volatility. It also stabilizes colloidal systems, making it ideal for developing nanomaterial formulations in academic and industrial R&D.
Product Operate Guide
Safe Dispensing
Use clean, dry tools (e.g., glass pipettes, stainless-steel spoons) to avoid contamination. For bulk use, connect to a closed transfer system—PEG-400’s low viscosity enables smooth pouring without clogs. Avoid direct contact with skin; wear gloves if handling large volumes.
Blending & Compatibility
Mix with water or oil-based ingredients at 20–40℃ (room temp preferred) for optimal dissolution. Stir gently until clear (typically 2–5 mins); avoid high-speed mixing to prevent air bubbles. Test small batches first when blending with new components.
Storage Tips
Seal tightly in original HDPE containers and store in a cool (15–25℃), dry area away from sunlight. Avoid freezing (may cause temporary cloudiness, but clarity returns at room temp). Check expiration date (36 months from production) before use.
FAQ
Q: Is PEG-400 safe for long-term use in pharmaceutical or food products?
A: Yes. With LD50 >20g/kg (oral toxicity) and compliance with USP/BP/FCC standards, it's recognized as safe for long-term use. It's metabolized and excreted without accumulation, making it suitable for chronic medication or daily food applications.
Q: What's the difference between Pharma Grade and Industrial Grade PEG-400? Can they be used interchangeably?
A: Pharma Grade has stricter impurity limits (e.g., aldehydes ≤0.005%) for safety, while Industrial Grade prioritizes cost-effectiveness. They're not interchangeable—using Industrial Grade in meds/food risks non-compliance and safety issues.
Q: Will PEG-400 change properties if stored below 0℃? How to restore it?
A: It may turn cloudy or form slight crystals below 0℃, but this doesn't damage its properties. Simply let it warm to 15–25℃ (room temp) and stir gently—clarity and functionality will fully recover.
Q: Can PEG-400 replace higher-molecular-weight PEGs (e.g., PEG-600, PEG-1000) in formulations?
A: It depends on viscosity needs. PEG-400 (37–45 cSt) is lower-viscosity than PEG-600 (90–110 cSt), so it works for thin liquids (serums, oral solutions) but not thick creams—test compatibility before replacement.
Q: Do you provide documentation to prove PEG-400's compliance with regional regulations (e.g., EU REACH, US FDA)?
A: Yes. We supply Certificates of Analysis (CoA) for each batch, plus REACH registration documents and FDA compliance statements, ensuring you meet regional standards for import and production.
