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Tween-80
Jienuo
Tween 80, also known as Polysorbate 80, is a widely - used non - ionic surfactant. Composed of polyoxyethylene sorbitan monooleate, it has excellent emulsifying capabilities, making it a go - to in various industries.
In food, it helps blend oil and water phases in products like ice - cream, preventing fat separation. In pharmaceuticals, it solubilizes poorly soluble drugs and serves as an emulsifier in oral or injectable medications. In cosmetics, Tween 80 is used to stabilize emulsions in lotions and creams, ensuring a smooth texture.
Product Advantage
1. Strong Emulsifying Capacity: Can emulsify 5-8 times its weight in oil (tested with vegetable oil and mineral oil), forming stable emulsions that remain uniform for over 60 days, reducing phase separation in food and cosmetic formulations.
2. Broad pH Compatibility: Maintains 90%+ activity in pH 3.0-10.0 (verified in 50+ formulations), suitable for acidic beverages and alkaline pharmaceutical suspensions without performance loss.
3. High Biocompatibility: Meets USP, EP, and FCC standards, with LD50 > 20g/kg (rat oral test), safe for use in pharmaceuticals (injectable grade) and food additives (daily intake ≤ 25mg/kg).
4. Excellent Thermal Stability: Retains 95% activity after 72 hours at 80℃, ensuring stability in high-temperature processing like pasteurization of dairy products and cosmetic emulsion preparation.
5. Low Foaming Property: Generates 60% less foam than anionic surfactants (measured by foam height method), ideal for low-foam applications such as oral liquid pharmaceuticals and clear cosmetic lotions.
Technical Parameters
| Parameter | Specification |
| Chemical Name | Polyoxyethylene (80) sorbitan monoaleate |
| Appearance | Yellow to amber viscous liquid |
| Lonicity | Non-ionic |
| Hydroxyl Value | 65-82 mg KOH/g |
| Saponification Value | 43~55 mg KOH/g |
| Acid Value | ≤ 2.0 mg KOH/g |
| Water Content | ≤ 3.0% |
| HLB Value | 15 |
| Flash Point | ≥ 140℃ |
| pH (5% aqueous solution) | 5.0-8.0 |
| Heavy Metals | ≤10 ppm |
Product Uses
1. Food Industry: As an emulsifier, it is used in ice cream, butter, etc., to evenly disperse fat particles, reduce ice crystal formation, and make the product have a delicate texture, extending the shelf life by 3-5 days (test data), meeting food-grade safety standards.
2. Medical Field: It helps insoluble drugs dissolve, improving bioavailability. For example, in vitamin injection solutions, it can increase drug stability by 98%, and is also used in oral emulsions to enhance absorption effects.
3. Cosmetics Industry: It is used in creams, lotions, etc., to stabilize the oil-water mixture system, prevent stratification, increase product smoothness, and in sunscreen lotions, it can promote the uniform distribution of active ingredients and enhance sun protection effects.
4. Biological Experiments: It is often used in cell culture as a dispersant to reduce cell aggregation. In protein extraction experiments, it can gently lyse cells without damaging the protein structure, with an experimental repeatability of over 90%.
Product Operate Guide
For Tween 80, add 0.5%-5% to formulations (adjust by use). Stir at 30-50℃ to dissolve fully. Mix with oil phase first for emulsions. Avoid strong oxidizers. Store sealed in a cool place. Stir gently if layered; no impact on performance.
FAQ
1. How to store Tween 80 properly?
Seal tightly and store at 15-30℃, away from sunlight and heat. It remains stable for 2 years. If it thickens in cold, warm gently to restore fluidity—no impact on performance.
2. What's the recommended dosage in food?
Typically 0.1%-0.5% of total formulation (e.g., 0.3% in ice cream). Exceeding 1% may cause off-flavors; follow local food additive regulations.
3. Is it safe for injectable pharmaceuticals?
Yes, pharmaceutical-grade Tween 80 meets USP/EP standards. Use 0.5%-2% in injections; ensure sterile handling to avoid contamination.
4. Can it mix with ionic surfactants?
Compatible with most non-ionic/anionic types. Avoid high concentrations of cationic surfactants—test 1:10 ratio first to prevent precipitation.