Industrial Grade Polyethylene Glycol 4000 (PEG 4000) - High Molecular Weight Binder & Plasticizer Supplier

Polyethylene Glycol 4000 (PEG - 4000) is a high - molecular - weight polymer with a general formula of H(OCH₂CH₂)ₙOH, where n is approximately 70 - 85. It appears as a white, odorless solid at room temperature, with a melting point around 50 - 58°C.

PEG - 4000 is highly soluble in water, forming clear solutions. It has a low toxicity and shows good biocompatibility. In the medical field, it is widely used as a laxative to relieve constipation by retaining water in the intestines, softening feces. In the pharmaceutical and cosmetic industries, it functions as a thickening agent, binder, and lubricant. Its excellent film - forming property also makes it suitable for coating tablets and capsules.

Product Advantage

1. Outstanding Molecular Weight Stability

PEG-4000 features a narrow molecular weight distribution with a coefficient of ≤1.05, significantly better than the industry average of 1.15. This ensures consistent performance across batches. After testing over 100 batches, the fluctuation of key indicators was less than 2%, providing a stable foundation for precise formulations in the pharmaceutical and chemical industries.

2. Superior Biocompatibility

Compliant with USP/EP pharmacopoeia standards, third-party testing shows a cytotoxicity grade of ≤1 and an allergenicity rate of <0.01%. It can be safely used in oral preparations, cosmetic bases, and other applications, demonstrating reliable biological safety in the biomedical field and making it an ideal alternative to traditional additives.

3. Efficient Solubility

At 25°C, its water solubility reaches 80g/100mL, and it is miscible with various organic solvents such as ethanol and propylene glycol. This broad solubility profile significantly enhances the dispersion efficiency of formulations. Experimental data shows that its solubilization effect is 15%-20% higher than that of ordinary PEG, reducing production time.

4. Excellent Process Adaptability

It has excellent thermal stability with a decomposition temperature of >250°C, and is not easily degraded during processes such as melting (60-70°C) and spray drying. Additionally, its solid powder form has good fluidity, with a stable bulk density of 0.55-0.60g/cm³, facilitating precise dosing in automated production lines.

5. High Purity Quality Assurance

Produced through a refined process, its purity is ≥99.5%, with ash content <0.01% and residual alcohol content <0.05%. A strict quality control system (ISO9001 certified) ensures extremely low impurities, making it particularly suitable for high-purity requirements in premium pharmaceutical excipients and electronic chemicals.

Technical Parameters

Product Uses

1. Pharmaceutical Formulations

Used as a binder in tablets and a solubilizer in oral suspensions. Its low toxicity and stable viscosity help control drug release rates, widely applied in sustained-release preparations.

2. Cosmetics & Personal Care

Acts as a humectant and thickener in creams, lotions, and shampoos. Improves product texture, enhances skin moisturization, and reduces irritation, suitable for sensitive skin formulations.

3. Food Industry

Functions as a lubricant in candy production and a stabilizer in dairy products. Complies with food-grade standards, preventing crystallization and extending shelf life of processed foods.

4. Industrial Applications

Serves as a lubricant and mold release agent in plastic and rubber processing. Reduces friction between materials, improving production efficiency and product surface quality.

5. Biotechnology

Used as a precipitant in protein purification and a cryoprotectant for cell cultures. Maintains biological activity of biomolecules during storage and processing.

Product Operate Guide

When using PEG-4000, wear gloves to avoid direct contact with skin. Weigh the required amount according to the formula, dissolve it at room temperature or by heating (≤60℃), and stir until uniform. Seal and store in a dry and well-ventilated place, away from fire sources. Do not store with strong oxidants. Wash hands after operation.. Store in a cool and dry place and use within 30 days after opening. In case of special problems, a technical team will provide a suitable solution within 24 hours.

FAQ

1. What are the uses of polyethylene glycol PEG-4000?

In industry, it is used as a lubricant, dispersant, etc.; in medicine, it can be used as a laxative, softening the feces by increasing intestinal moisture. It should be noted that different grades have different uses and cannot be mixed.

2. What should be paid attention to when storing PEG-4000?

It needs to be sealed and stored in a dry and ventilated place to avoid moisture and caking. Keep away from fire sources and strong oxidants. It can be stored at room temperature without the need for refrigeration. It is better to be kept out of reach of children.

3. What should be done if skin comes into contact with PEG-4000 during use?

Immediately rinse the affected area with clean water. PEG-4000 is less irritating and generally causes no major problems. If there is redness, itching, etc., wash with soap water and seek medical attention promptly.

4. What are the differences between different molecular weights of PEG?

Different molecular weights have different physical properties. PEG-4000 is a solid, while molecules with smaller weights such as PEG-200 are liquids. Their uses also vary depending on their characteristics.