Polyethylene Glycol (PEG)-2000, with CAS No. 25322-68-3, is a linear polyether featuring an average molecular weight of 2000. It presents as a white, free-flowing solid powder or flakes, boasting excellent water solubility, non-ionic properties, low toxicity, and strong chemical stability.
Widely applied as a pharmaceutical excipient, cosmetic ingredient, and industrial additive, it delivers core functions: acting as a binder for formulation cohesion, a lubricant to prevent sticking, a humectant to retain moisture, and a plasticizer to enhance flexibility. Its good compatibility and low irritation make it reliable for pharmaceuticals, skincare, food processing, and plastic/rubber industries.
Product Advantage
1. Premium Purity with Global Pharmacopoeia Compliance
Our PEG-2000 achieves ≥99.6% purity, with ethylene glycol/diethylene glycol impurities controlled below 0.08%—surpassing USP, EP, and BP standards. Each batch passes 15+ strict tests (e.g., molecular weight, pH, moisture), ensuring safe use in pharmaceuticals, food, and cosmetics, and meeting regulatory requirements of 80+ countries.
2. Narrow Molecular Weight Distribution for Consistent Performance
With a polydispersity index (PDI) of ≤1.04, our PEG-2000 maintains uniform physical/chemical properties across batches. This stability reduces formulation errors by 12% for customers, as it ensures consistent binding strength in tablets and moisture retention in creams, avoiding batch-to-batch performance fluctuations.
3. Low Irritation & High Biocompatibility for Sensitive Applications
Toxicity tests confirm an oral LD50 (rat) of >6000 mg/kg (classified as non-toxic), and skin irritation tests show 0% redness/itching reactions. It's safe for long-term use in baby skincare, oral medications, and eye drops, making it a preferred choice for brands focusing on safety.
4. Versatile Functionality Across Industries
Beyond core roles (binder, lubricant, humectant), it offers customized benefits: in plastic processing, it lowers melting temperature by 5-8% (saving energy); in coatings, it improves film leveling by 18%; in food, it extends shelf life by 35%. This versatility cuts customers’ need for multiple additives, reducing costs by 10-15%.
5. Strict Quality Control & Full Traceability
We maintain a 100% qualified rate for 6 consecutive years, supported by a real-time traceability system. Each unit comes with a report covering raw material sources, production dates, and inspection data, enabling customers to easily pass audits from authorities like the FDA and EU EMA.
Technical Parameters
| Parameter | Details |
| Appearance | White to off-white powder or crystals |
| Color | ≤50 |
| Hydroxyl value | 51~63 |
| Molecular Weight | 1800~2200 |
| pH Value | 4.5-7.0 |
| Purity | ≥ 99.0% |
Product Uses
1. Pharmaceutical Industry
As a key excipient, it's used in oral tablets/capsules: acts as a binder to improve powder cohesion (reducing tablet breakage rate), a lubricant to prevent die sticking, and a coating material to enhance drug stability. Also added to topical ointments to adjust texture and boost drug solubility.
2. Cosmetic & Skincare Sector
Applied in creams, lotions, and lipsticks: works as a humectant to lock in moisture (extending skin hydration for 5-7 hours), a plasticizer to keep lipsticks soft and non-cracking, and a solubilizer to blend oil-water ingredients. Ideal for sensitive skin products due to low irritation.
3. Food Processing Field
Used in baked goods, candies, and dairy products: acts as a humectant to prevent staling (extending shelf life by 25-35%), a plasticizer to improve candy chewiness, and a lubricant in powdered food to avoid caking. Complies with FDA and EU food-grade standards.
4. Plastic & Rubber Processing
Serves as an internal lubricant in PVC and rubber production: reduces friction between polymer molecules, lowers melting temperature (saving energy by 7-9%), and improves product surface gloss. Doesn’t affect the mechanical strength of final plastic/rubber products.
5. Coating & Paint Industry
Added to water-based coatings: functions as a dispersant to keep pigments uniformly distributed (preventing sedimentation), a plasticizer to enhance film flexibility (reducing cracking in low temperatures), and a leveling agent to improve coated surface smoothness.
Product Operate Guide
1. Prep: For solid mixes (e.g., tablet excipients), blend dry PEG-2000 powder with other ingredients at 20-25℃ (avoid humidity). For liquids (e.g., creams), dissolve it in 40-50℃ water first, then stir into the base.
2. Dosage: Use 2-12% of total formulation (3-6% as lubricant/binder, 5-10% as humectant/plasticizer; adjust per need).
3. Storage: Keep in sealed, dry containers away from sunlight. Use within 24 months of production for best results.
FAQ
1. Q: Can PEG-2000 dissolve in solvents other than water?
A: It dissolves well in water, and also in some polar organic solvents like ethanol and glycerin. But it’s insoluble in non-polar solvents such as oil. Test a small amount first if using uncommon solvents.
2. Q: Is PEG-2000 safe for use in baby food or skincare products?
A: Yes. It meets food and cosmetic grade standards (e.g., FDA, USP), has low toxicity and no skin irritation, making it safe for baby-related products when used within the recommended 2-12% dosage.
3. Q: What if PEG-2000 gets damp and forms lumps?
A: Mild lumps can be crushed into powder and used normally—dampness won’t change its properties. For severe lumping, dry it at 35-45℃ for 1 hour, then cool before blending into formulations.
4. Q: Can PEG-2000 replace PEG-1500 or PEG-3350 in my formulation?
A: Not directly. PEG-2000 has a higher molecular weight than PEG-1500 (harder texture) and lower than PEG-3350 (softer than PEG-3350). Adjust based on your need for flexibility, solubility, or binding strength.
