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Home » Products » Chemical Series » Polyether series » Polyethylene Glycol Monomethyl Ether MPEG Series » MPEG-200 Polyethylene Glycol Monomethyl Ether - Biocompatible for Pharmaceutical & Cosmetic Formulations

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MPEG-200 Polyethylene Glycol Monomethyl Ether - Biocompatible for Pharmaceutical & Cosmetic Formulations

Polyethylene Glycol Monomethyl Ether (MPEG-200), a non-ionic ethylene oxide-methyl ether polymer (CAS 9004-74-4), is a colorless to light yellow transparent liquid (25°C) with pH 5.0-7.0 and hydroxyl value 255-312 mgKOH/g. It's highly water/ethanol-soluble, low-viscosity, and thermally stable, serving as a versatile surfactant, thickener, and raw material across industries.
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Polyethylene Glycol Monomethyl Ether (MPEG-200)- Product Overview

Polyethylene Glycol Monomethyl Ether (MPEG-200, CAS 9004-74-4) is a high-purity non-ionic polymer with a molecular weight of ~200. Featuring excellent water solubility, low viscosity, and strong hydrophilicity, it exhibits good biocompatibility and stability under neutral conditions. As a versatile raw material, it acts as a surfactant, solubilizer, and lubricant, enhancing solubility, dispersion, and product stability. Widely applied in pharmaceuticals (excipients), cosmetics, polymer synthesis, detergents, coatings, and lubricants, our MPEG-200 meets industrial/food/pharmaceutical grade standards, delivering consistent quality for diverse industrial and commercial needs.


Product Advantage

  1. Exceptional Solubility & Compatibility

    MPEG-200 dissolves easily in water, ethanol, and organic solvents (no precipitation), while its neutral pH (5.0-7.0) ensures compatibility with most formulations—ideal for mixing with surfactants, polymers, or cosmetic ingredients without causing instability.

  2. Controlled Hydroxyl Value for Precision Reactions

    With a strictly controlled hydroxyl value range (255-312 mgKOH/g), it enables consistent reactivity in synthesis (e.g., with acrylic acid), ensuring batch-to-batch stability for downstream products like polycarboxylate superplasticizers.

  3. Low Viscosity & Easy Handling

    As a low-molecular-weight (≈200) transparent liquid, MPEG-200 flows smoothly, reducing pumping/processing effort in production lines. Its liquid form also simplifies dosage adjustment compared to solid MPEG grades.

  4. Thermal Stability for Wide Processing Conditions

    It maintains structural stability under high temperatures (no decomposition), making it suitable for heat-intensive processes (e.g., coating curing, polymer polymerization) without losing performance.


Technical Specifications 

Technical Parameter
Specification (MPEG-200)
Chemical Name
Polyethylene Glycol Monomethyl Ether 200
CAS Number
9004-74-4
Chemical Composition
Methyl ether-ethylene oxide polymer
Type
Non-ionic
Appearance (25°C)
Colorless to light yellow transparent liquid
Molecular Weight (Average)
~200
pH Value (1% aqueous solution)
5.0 - 7.0 (neutral)
Hydroxyl Value
255 - 312 mgKOH/g (strictly controlled for reaction consistency)
Water Solubility
Fully soluble in water (no precipitation at 20 - 40°C)
Organic Solvent Compatibility
Soluble in ethanol, acetone, and most polar organic solvents
Viscosity (25°C)
≤ 50 mPa·s (low viscosity for easy handling)
Moisture Content
≤ 0.5% (max, to avoid formulation instability)
Ash Content
≤ 0.1% (high purity, minimal impurities)
Thermal Stability
Stable at ≤ 120°C (no decomposition under typical processing temperatures)
Flash Point
≥ 150°C (safe for industrial storage/handling)
Grade Options
Industrial Grade, Cosmetic Grade, Pharmaceutical Grade
Shelf Life (Sealed)
3 years (when stored in dry, ventilated conditions)


Product Uses

  1. Surfactant & Detergent Additive

    MPEG-200 acts as a non-ionic surfactant in metalworking fluids, enhancing cleaning power and emulsification. It's also added to detergents to boost dispersion of dirt particles in water.

  2. Cosmetic Formulation Ingredient

    Its mildness and moisturizing properties make it a thickener/consistency regulator in lotions, creams, and toothpaste—improving product texture and spreading ability.

  3. Polymer Synthesis Raw Material

    It reacts with acrylic acid to produce MPEG methacrylate, a core monomer for polycarboxylate superplasticizers (used to enhance concrete workability and strength).


Product Operate Guide

For general blending: Add MPEG-200 directly to formulations (e.g., detergents, cosmetics) under stirring (20-40°C) until fully dissolved. For synthesis (e.g., superplasticizer production): Use it in a 1:1 molar ratio with acrylic acid, reacting at 80-90°C with a catalyst (e.g., hydroquinone) to ensure complete polymerization. Store in a dry, ventilated area (shelf life: 3 years).


FAQ

  1. What's the shelf life of MPEG-200?

    It has a 3-year shelf life when stored in sealed, dry, and ventilated conditions (avoid direct sunlight and moisture). Unsealed containers should be used within 6 months to prevent contamination.

  2. Is MPEG-200 safe for cosmetic use?

    Yes—its neutral pH and mild nature meet cosmetic-grade standards, making it suitable for skincare and personal care products (no irritation risk in typical concentrations).

  3. Can MPEG-200 replace solid MPEG grades?

    It's ideal for liquid formulations (e.g., detergents, lotions) due to its liquid form, but solid MPEG (e.g., MPEG-1000) is better for solid products (e.g., tablets).


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